Surgery of advanced melanoma. Are we facing a turning point?

Surgical treatment of metastatic melanoma has been evolving for over 100 years towards an increasingly less radical treatment, and therefore, with less impact on a patient’s quality of life.

Numerous studies analyzing the survival outcomes of patients undergoing surgery for metastatic melanoma have failed to show a clear-cut overall survival benefit. Moreover, recent hypotheses of metastatic spread and, particularly, the incorporation of immunotherapy and targeted therapies, are changing the indications and surgical techniques used for the treatment of patients with metastatic melanoma.

The plenary will review the current recommendations for the surgical treatment of metastatic nodal disease and the expected developments in surgical interventions for advanced melanoma; a surgical approach that will, almost certainly, be increasingly less radical and combined with neoadjuvant immunotherapy options that will soon be available.

David Moreno-Ramírez, PhD, Prof.

David Moreno-Ramírez is Professor of Dermatology in the University of Sevilla and present Chair of the Medical-Surgical Dermatology Unit at the Hospital Universitario Virgen Macarena (Seville-Spain).

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